101 Results for "

γ-aminobutyric acid (GABA)

" in MedChemExpress (MCE) Product Catalog:
Products (101)

101 Results for "γ-aminobutyric acid (GABA)" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-B0007
CAS No.: 1134-47-0
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist with blood-brain barrier permeability. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research .
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13
13 Publications Verification
Cat. No.: HY-B0007C
CAS No.: 28311-31-1
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Baclofen hydrochloride, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen hydrochloride mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen hydrochloride has high blood brain barrier penetrance. Baclofen hydrochloride has the potential for muscle spasticity research .
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5
5 Cited Publications
Cat. No.: HY-N0067
CAS No.: 56-12-2
Synonyms: 4-aminobutyric acid
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .
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3
3 Cited Publications
Cat. No.: HY-N7110
CAS No.: 6665-83-4
6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS (HY-D1056) -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin (BHb) glycosylation. 6-Hydroxyflavone has a kidney protective effect. In addition, 6-Hydroxyflavone enhances GABA-induced current through the Benzodiazepine sites of γ-aminobutyric acid (GABAA) receptors. 6-Hydroxyflavone shows a clear preference for α2 - and α3 - subtypes, which play an anti-anxiety role .
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2
2 Cited Publications
Cat. No.: HY-N0067S
CAS No.: 70607-85-1
Synonyms: 4-aminobutyric acid-d6
γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain , binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors) .
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2
2 Cited Publications
Cat. No.: HY-B1122
CAS No.: 339-72-0
Synonyms: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains .
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2
2 Cited Publications
Cat. No.: HY-W007686
CAS No.: 3251-69-2
Synonyms: Imidazolyl-4-acetic acid hydrochloride
Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain .
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1
1 Cited Publications
Cat. No.: HY-B1715
CAS No.: 62613-82-5
Synonyms: ISF2522
Oxiracetam (ISF2522) is an orally active and a BBB-penetrable cyclic derivative of γ-aminobutyric acid (GABA). Oxiracetam reaches the hippocampus and cerebral cortex in high concentrations. Oxiracetam can promote cognitive function and regulate inflammatory response, with powerful neuroprotective effects. Oxiracetam can be used in the study of central nervous system diseases .
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1
1 Cited Publications
Cat. No.: HY-W015878
CAS No.: 660-88-8
5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.
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1
1 Cited Publications
Cat. No.: HY-B0585
CAS No.: 7491-74-9
Synonyms: UCB-6215
Target:  

iGluR

Research Areas:  

Neurological Disease

Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.
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1
1 Cited Publications
Cat. No.: HY-16974
CAS No.: 1093861-60-9
Research Areas:  

Infection

Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod .
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1
1 Cited Publications
Cat. No.: HY-N2368
CAS No.: 499-04-7
Arecaidine is a GABA transport system inhibitor. Arecaidine inhibits the proliferation of oral mucosal fibroblasts, increases the secretion of IL-6, TGF-β and TNF-α in cells, downregulates the expression of PPAR-γ and PCK1 in cells, and upregulates the expression of TGF-β1 . Arecaidine inhibits the uptake of γ-aminobutyric acid and β-alanine by the central nervous system of cats . Arecaidine inhibits hPAT1-mediated L-[ 3H]proline uptake in cells. Arecaidine can be used in research related to neurological diseases .
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1
1 Cited Publications
Cat. No.: HY-N8157
CAS No.: 1464-33-1
4'-O-Methylpyridoxine is an orally active antivitamin B6 compound found in Ginkgo biloba seeds and leaves. 4'-O-Methylpyridoxine inhibits pyridoxal kinase. 4'-O-Methylpyridoxine reduces brain pyridoxal-5'-phosphate (PLP) levels, decreases gamma-aminobutyric acid/glutamate (GABA/Glu) ratio. 4'-O-Methylpyridoxine increases plasma levels of pyridoxal-5'-phosphate and pyridoxal. 4'-O-Methylpyridoxine induces hyperactivity, convulsions, pathological tissue changes, organ damage in rodent brain and heart .
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1
1 Cited Publications
Cat. No.: HY-17599
CAS No.: 144-29-6
Synonyms: 1,4-Diazacyclohexane citrate
Target:  

GABA Receptor Parasite

Research Areas:  

Infection

Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist . Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities .
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Cat. No.: HY-B0340
CAS No.: 77191-36-7
Synonyms: DM9384; DZL-221
Nefiracetam is a cognition-enhancing agent. Nefiracetam is an activator of nAChR, N-methyl-D-aspartate receptor (NMDAR), mGluR5, PKC, gamma-aminobutyric acid (GABA), and N/L-type Ca 2+ channels. Nefiracetam promotes neuroplasticity and enhances neuroprotection. Nefiracetam can be used in Alzheimer's disease, epilepsy, and cerebral ischemia research .
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Cat. No.: HY-N0067R
CAS No.: 56-12-2
Synonyms: 4-aminobutyric acid (Standard)
γ-Aminobutyric acid (Standard) is the analytical standard of γ-Aminobutyric acid. This product is intended for research and analytical applications. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors. γ-Aminobutyric acid shows calming effect by blocking specific signals of central nervous system .
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Cat. No.: HY-109077
CAS No.: 1621436-41-6
Purity:  98.53%
Synonyms: BAY-1272858
Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity .
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Cat. No.: HY-B1427
CAS No.: 924-49-2
Synonyms: Gamma-amino-beta-hydroxybutyric acid
Gamibetal (Gamma-amino-beta-hydroxybutyric acid) is γ-amino-β-hydroxybutyric acid (GABOB), a hydroxylated derivative of GABA (γ-aminobutyric acid). Gamibetal exhibits central inhibitory and anticonvulsant activities. Gamibetal can be used in research on epilepsy, neuralgia, and other conditions .
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Cat. No.: HY-107482
CAS No.: 34562-97-5
Purity:  98.25%
Synonyms: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .
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Cat. No.: HY-A0173
CAS No.: 62666-20-0
Synonyms: SL 76002
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Progabide is a gamma-aminobutyric acid receptor (GABA) agonist.
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